EDUCATION

Undergraduate Degree

  • Northwestern University , 1996 , Evanston , IL

Medical School

  • University of Michigan Medical School , 2000 , Ann Arbor , MI

Residency

Orthopedic Surgery
  • Harvard Combined Orthopedic Residency Program , 2005 , Boston , MA

Fellowship

Pediatric Orthopedic Surgery
  • Boston Children's Hospital , 2006 , Boston , MA

Philosophy of Care

Outside of Boston Children’s Hospital, I provide community outreach and teaching at a national level through the following condition specific patient organizations:

  • Little People of America (participation in the yearly national meetings with invited talks and meetings with their medical advisory board);
  • Osteogenesis Imperfecta Foundation (participation in Walk for OI  yearly fundraiser event as medical expert, participation in scientific invited meeting);
  • CLOVES Foundation (on medical advisory board).

PROFESSIONAL HISTORY

Dr. Samantha Spencer has been a pediatric orthopedic surgeon on staff at Boston Children’s Hospital since August, 2006. She treats patients from birth to adult for a wide range of congenital and traumatic conditions, both surgically and non-surgically. Her particular interests include lower extremity disorders such as clubfeet and congenital limb differences, osteogenesis imperfecta and other bone dysplasias as well as vascular anomalies.

Dr. Spencer works with our multidisciplinary programs in Osteogenesis Imperfecta, Ehlers Danlos, and extensively with the Vascular Anomalies Center. Her clinical research focuses on congenital lower extremity, bone dysplasias and vascular anomalies. She also participates in the Lower Extremity Team research group meetings and projects.

CERTIFICATIONS

  • American Board of Orthopaedic Surgery, General Orthopaedics

PUBLICATIONS

Publications powered by Harvard Catalyst Profiles

  1. Prospective Evaluation of Tarsal Coalition Excision Show Significant Improvements in Pain and Function. J Pediatr Orthop. 2021 Oct 01; 41(9):e828-e832. View abstract
  2. Surgical Treatment of Solitary Periarticular Osteochondromas About the Knee in Pediatric and Adolescent Patients: Complications and Functional Outcomes. J Bone Joint Surg Am. 2021 Jul 21; 103(14):1276-1283. View abstract
  3. Best practice guidelines in managing the craniofacial aspects of skeletal dysplasia. Orphanet J Rare Dis. 2021 01 14; 16(1):31. View abstract
  4. The MITF paralog tfec is required in neural crest development for fate specification of the iridophore lineage from a multipotent pigment cell progenitor. PLoS One. 2021; 16(1):e0244794. View abstract
  5. Classification of lower extremity venous malformations and risk of knee involvement: A retrospective cohort study. J Am Acad Dermatol. 2021 Jan 06. View abstract
  6. College of American Pathologists Cancer Protocols: From Optimizing Cancer Patient Care to Facilitating Interoperable Reporting and Downstream Data Use. JCO Clin Cancer Inform. 2021 01; 5:47-55. View abstract
  7. Orthopedic issues in vascular anomalies. Semin Pediatr Surg. 2020 Oct; 29(5):150973. View abstract
  8. Mitf-family transcription factor function is required within cranial neural crest cells to promote choroid fissure closure. Development. 2020 07 13; 147(21). View abstract
  9. Best practice guidelines for management of spinal disorders in skeletal dysplasia. Orphanet J Rare Dis. 2020 06 24; 15(1):161. View abstract
  10. Surgical Management of Fibroadipose Vascular Anomaly of the Lower Extremities. J Pediatr Orthop. 2020 Mar; 40(3):e227-e236. View abstract
  11. Sodium-Calcium Exchangers of the SLC8 Family in Oligodendrocytes: Functional Properties in Health and Disease. Neurochem Res. 2020 Jun; 45(6):1287-1297. View abstract
  12. Fibroadipose Vascular Anomaly in the Upper Extremity: A Distinct Entity With Characteristic Clinical, Radiological, and Histopathological Findings. J Hand Surg Am. 2020 Jan; 45(1):68.e1-68.e13. View abstract
  13. Pulmonary thromboembolic events in patients with congenital lipomatous overgrowth, vascular malformations, epidermal nevi, and spinal/skeletal abnormalities and Klippel-Trénaunay syndrome. J Vasc Surg Venous Lymphat Disord. 2018 07; 6(4):511-516. View abstract
  14. Preoperative Embolization of Venous Malformations Using n-Butyl Cyanoacrylate. Vasc Endovascular Surg. 2018 May; 52(4):269-274. View abstract
  15. Subtalar Coalitions: Does the Morphology of the Subtalar Joint Involvement Influence Outcomes After Coalition Excision? J Foot Ankle Surg. 2017 Jul - Aug; 56(4):797-801. View abstract
  16. Uniplanar Versus Taylor Spatial Frame External Fixation For Pediatric Diaphyseal Tibia Fractures: A Comparison of Cost and Complications. J Pediatr Orthop. 2016 Dec; 36(8):821-828. View abstract
  17. Musculoskeletal Conditions in a Pediatric Population with Ehlers-Danlos Syndrome. J Pediatr. 2017 02; 181:261-266. View abstract
  18. Treatment dilemma in multiple metatarsal fractures: when to operate? J Pediatr Orthop B. 2016 Jul; 25(4):354-60. View abstract
  19. Treatment outcomes after insufficiency femoral diaphyseal fractures in nonambulatory children. J Pediatr Orthop B. 2016 Jul; 25(4):331-7. View abstract
  20. Cryoablation in fibro-adipose vascular anomaly (FAVA): a minimally invasive treatment option. Pediatr Radiol. 2016 Jul; 46(8):1179-86. View abstract
  21. Response: "Best practices in the evaluation and treatment of foramen magnum stenosis in achondroplasia during infancy" and "Is there a correlation between sleep disordered breathing and foramen magnum stenosis in children with achondroplasia?". . 2016 Apr; 170A(4):1101-3. View abstract
  22. Surgical Treatment of Spinal Deformity in Patients With CLOVES Syndrome: A Report of 4 Cases. J Pediatr Orthop. 2015 Oct-Nov; 35(7):682-6. View abstract
  23. Best practices in the evaluation and treatment of foramen magnum stenosis in achondroplasia during infancy. . 2016 Jan; 170A(1):42-51. View abstract
  24. Patient-reported Outcomes of Tarsal Coalitions Treated With Surgical Excision. J Pediatr Orthop. 2015 Sep; 35(6):583-8. View abstract
  25. Likelihood of surgery in isolated pediatric fifth metatarsal fractures. J Pediatr Orthop. 2015 Apr-May; 35(3):296-302. View abstract
  26. Lymphatic and other vascular malformative/overgrowth disorders are caused by somatic mutations in PIK3CA. J Pediatr. 2015 Apr; 166(4):1048-54.e1-5. View abstract
  27. Cancer biomarkers: the role of structured data reporting. Arch Pathol Lab Med. 2015 May; 139(5):587-93. View abstract
  28. Complications after modified Dunn osteotomy for the treatment of adolescent slipped capital femoral epiphysis. J Pediatr Orthop. 2014 Oct-Nov; 34(7):661-7. View abstract
  29. Satisfactory patient-based outcomes after surgical treatment for idiopathic clubfoot: includes surgeon's individualized technique. J Pediatr Orthop. 2014 Sep; 34(6):631-8. View abstract
  30. Orthopedic issues in vascular anomalies. Semin Pediatr Surg. 2014 Aug; 23(4):227-32. View abstract
  31. Fibro-adipose vascular anomaly: clinical-radiologic-pathologic features of a newly delineated disorder of the extremity. J Pediatr Orthop. 2014 Jan; 34(1):109-17. View abstract
  32. Prospective evaluation of a prenatal sonographic clubfoot classification system. Fetal Diagn Ther. 2013; 34(4):236-40. View abstract
  33. Introducing new College of American Pathologists reporting templates for cancer biomarkers. Arch Pathol Lab Med. 2014 Feb; 138(2):157-8. View abstract
  34. Proximal tibial osteotomy and Taylor Spatial Frame application for correction of tibia vara in morbidly obese adolescents. J Pediatr Orthop. 2013 Apr-May; 33(3):276-81. View abstract
  35. Painful pes planovalgus: an uncommon pediatric orthopedic presentation of Charcot-Marie-Tooth disease. J Pediatr Orthop B. 2012 Sep; 21(5):428-33. View abstract
  36. Somatic mosaic activating mutations in PIK3CA cause CLOVES syndrome. Am J Hum Genet. 2012 Jun 08; 90(6):1108-15. View abstract
  37. Primary lyme arthritis of the pediatric hip. J Pediatr Orthop. 2011 Oct-Nov; 31(7):787-90. View abstract
  38. Misdiagnosis of knee venous malformation as juvenile idiopathic arthritis. J Pediatr Orthop. 2011 Sep; 31(6):683-90. View abstract
  39. Complications of talus fractures in children. J Pediatr Orthop. 2010 Dec; 30(8):779-84. View abstract
  40. Prenatally diagnosed clubfeet: comparing ultrasonographic severity with objective clinical outcomes. J Pediatr Orthop. 2010 Sep; 30(6):606-11. View abstract
  41. Capital realignment for moderate and severe SCFE using a modified Dunn procedure. Clin Orthop Relat Res. 2009 Mar; 467(3):704-16. View abstract
  42. Surgical dislocation in the management of pediatric and adolescent hip deformity. Clin Orthop Relat Res. 2009 Mar; 467(3):724-31. View abstract
  43. Early results of treatment of hip impingement syndrome in slipped capital femoral epiphysis and pistol grip deformity of the femoral head-neck junction using the surgical dislocation technique. J Pediatr Orthop. 2006 May-Jun; 26(3):281-5. View abstract